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Increased 4R tau expression and behavioural changes in a novel MAPT-N296H genomic mouse model of tauopathy
The microtubule-associated protein tau is implicated in various neurodegenerative diseases including Alzheimer’s disease, progressive supranuclear palsy and corticobasal degeneration, which are characterized by intracellular accumulation of hyperphosphorylated tau. Mutations in the tau gene MAPT cau...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5324134/ https://ncbi.nlm.nih.gov/pubmed/28233851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43198 |
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