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Knock-out and transgenic mouse models of tauopathies

Tauopathies, characterized by the dysfunction and aggregation of the microtubule-associated protein tau (MAPT), represent some of the most devastating neurodegenerative disorders afflicting the elderly, including Alzheimer's disease and progressive supranuclear palsy. Here we review the range o...

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Detalhes bibliográficos
Main Authors: Denk, Franziska, Wade-Martins, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806682/
https://ncbi.nlm.nih.gov/pubmed/17590238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2007.05.010
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