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Bromodomain and Extra-Terminal Protein Inhibition Attenuates Neutrophil-dominant Allergic Airway Disease

Atopic asthma is a prevalent respiratory disease that is characterized by inflammation, mucus hypersecretion, and airway hyperresponsiveness. The complexity of this heterogeneous disorder has commanded the need to better define asthma phenotypes based on underlying molecular mechanisms of disease. A...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Manni, Michelle L., Mandalapu, Sivanarayana, Salmeron, Andres, Lora, Jose M., Kolls, Jay K., Alcorn, John F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324049/
https://ncbi.nlm.nih.gov/pubmed/28233801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43139
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