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Bromodomain and Extra-Terminal Protein Inhibition Attenuates Neutrophil-dominant Allergic Airway Disease

Atopic asthma is a prevalent respiratory disease that is characterized by inflammation, mucus hypersecretion, and airway hyperresponsiveness. The complexity of this heterogeneous disorder has commanded the need to better define asthma phenotypes based on underlying molecular mechanisms of disease. A...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Manni, Michelle L., Mandalapu, Sivanarayana, Salmeron, Andres, Lora, Jose M., Kolls, Jay K., Alcorn, John F.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324049/
https://ncbi.nlm.nih.gov/pubmed/28233801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43139
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