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Bromodomain and Extra-Terminal Protein Inhibition Attenuates Neutrophil-dominant Allergic Airway Disease

Atopic asthma is a prevalent respiratory disease that is characterized by inflammation, mucus hypersecretion, and airway hyperresponsiveness. The complexity of this heterogeneous disorder has commanded the need to better define asthma phenotypes based on underlying molecular mechanisms of disease. A...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Manni, Michelle L., Mandalapu, Sivanarayana, Salmeron, Andres, Lora, Jose M., Kolls, Jay K., Alcorn, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324049/
https://ncbi.nlm.nih.gov/pubmed/28233801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43139
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