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T-cell epitope strength in WAP-T mouse mammary carcinomas is an important determinant in PD1/PD-L1 immune checkpoint blockade therapy
Using the SV40 transgenic WAP-T/WAP-T(NP) mouse models for mammary carcinomas, we compared the response to immune checkpoint blockade therapy in tumor mice expressing either SV40 T-antigen containing the LCMV NP-epitope (T-Ag(NP) in WAP-T(NP) mice), or the unmodified T-antigen (T-Ag in WAP-T mice)....
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5323098/ https://ncbi.nlm.nih.gov/pubmed/27579535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11620 |
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