Tumorigenic WAP-T Mouse Mammary Carcinoma Cells: A Model for a Self-Reproducing Homeostatic Cancer Cell System

BACKGROUND: In analogy to normal stem cell differentiation, the current cancer stem cell (CSC) model presumes a hierarchical organization and an irreversible differentiation in tumor tissue. Accordingly, CSCs should comprise only a small subset of the tumor cells, which feeds tumor growth. However,...

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Main Authors: Wegwitz, Florian, Kluth, Mark-Andreas, Mänz, Claudia, Otto, Benjamin, Gruner, Katharina, Heinlein, Christina, Kühl, Marion, Warnecke, Gabriele, Schumacher, Udo, Deppert, Wolfgang, Tolstonog, Genrich V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920333/
https://ncbi.nlm.nih.gov/pubmed/20730114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012103
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