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An inducible transgenic mouse breast cancer model for the analysis of tumor antigen specific CD8(+) T-cell responses

In Simian virus 40 (SV40) transgenic BALB/c WAP-T mice tumor development and progression is driven by SV40 tumor antigens encoded by inducible transgenes. WAP-T mice constitute a well characterized mouse model for breast cancer with strong similarities to the corresponding human disease. BALB/c mice...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bruns, Michael, Wanger, Jara, Utermöhlen, Olaf, Deppert, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770716/
https://ncbi.nlm.nih.gov/pubmed/26513294
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