Simian Virus 40 Large-T-Antigen-Specific Rejection of mKSA Tumor Cells in BALB/c Mice Is Critically Dependent on both Strictly Tumor-Associated, Tumor-Specific CD8(+) Cytotoxic T Lymphocytes and CD4(+) T Helper Cells

Protective immunity of BALB/c mice immunized with simian virus 40 (SV40) large T antigen (TAg) against SV40-transformed, TAg-expressing mKSA tumor cells is critically dependent on both CD8(+) and CD4(+) T lymphocytes. By depleting mice of T-cell subsets at different times before and after tumor chal...

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Detalhes bibliográficos
Main Authors: Utermöhlen, Olaf, Schulze-Garg, Christine, Warnecke, Gabriele, Gugel, Roland, Löhler, Jürgen, Deppert, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114641/
https://ncbi.nlm.nih.gov/pubmed/11602701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.10593-10602.2001
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