The intron in centromeric noncoding RNA facilitates RNAi-mediated formation of heterochromatin

In fission yeast, the formation of centromeric heterochromatin is induced through the RNA interference (RNAi)-mediated pathway. Some pre-mRNA splicing mutants (prp) exhibit defective formation of centromeric heterochromatin, suggesting that splicing factors play roles in the formation of heterochrom...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Mutazono, Masatoshi, Morita, Misato, Tsukahara, Chihiro, Chinen, Madoka, Nishioka, Shiori, Yumikake, Tatsuhiro, Dohke, Kohei, Sakamoto, Misuzu, Ideue, Takashi, Nakayama, Jun-ichi, Ishii, Kojiro, Tani, Tokio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322907/
https://ncbi.nlm.nih.gov/pubmed/28231281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006606
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