ALKBH7 Variant Related to Prostate Cancer Exhibits Altered Substrate Binding

The search for prostate cancer biomarkers has received increased attention and several DNA repair related enzymes have been linked to this dysfunction. Here we report a targeted search for single nucleotide polymorphisms (SNPs) and functional impact characterization of human ALKBH family dioxygenase...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Walker, Alice R., Silvestrov, Pavel, Müller, Tina A., Podolsky, Robert H., Dyson, Gregory, Hausinger, Robert P., Cisneros, Gerardo Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322872/
https://ncbi.nlm.nih.gov/pubmed/28231280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005345
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