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Validation of an NGS mutation detection panel for melanoma
BACKGROUND: Knowledge of the genotype of melanoma is important to guide patient management. Identification of mutations in BRAF and c-KIT lead directly to targeted treatment, but it is also helpful to know if there are driver oncogene mutations in NRAS, GNAQ or GNA11 as these patients may benefit fr...
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| Pubblicato in: | BMC Cancer |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5322598/ https://ncbi.nlm.nih.gov/pubmed/28228113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3149-0 |
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