Use of the QIAGEN GeneReader NGS system for detection of KRAS mutations, validated by the QIAGEN Therascreen PCR kit and alternative NGS platform

BACKGROUND: The detection of somatic mutations in primary tumors is critical for the understanding of cancer evolution and targeting therapy. Multiple technologies have been developed to enable the detection of such mutations. Next generation sequencing (NGS) is a new platform that is gradually beco...

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Vydáno v:BMC Cancer
Hlavní autoři: Darwanto, Agus, Hein, Anne-Mette, Strauss, Sascha, Kong, Yi, Sheridan, Andrew, Richards, Dan, Lader, Eric, Ngowe, Monika, Pelletier, Timothy, Adams, Danielle, Ricker, Austin, Patel, Nishit, Kühne, Andreas, Hughes, Simon, Shiffman, Dan, Zimmermann, Dirk, te Kaat, Kai, Rothmann, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441096/
https://ncbi.nlm.nih.gov/pubmed/28532404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3328-z
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