Use of the QIAGEN GeneReader NGS system for detection of KRAS mutations, validated by the QIAGEN Therascreen PCR kit and alternative NGS platform

BACKGROUND: The detection of somatic mutations in primary tumors is critical for the understanding of cancer evolution and targeting therapy. Multiple technologies have been developed to enable the detection of such mutations. Next generation sequencing (NGS) is a new platform that is gradually beco...

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Gepubliceerd in:BMC Cancer
Hoofdauteurs: Darwanto, Agus, Hein, Anne-Mette, Strauss, Sascha, Kong, Yi, Sheridan, Andrew, Richards, Dan, Lader, Eric, Ngowe, Monika, Pelletier, Timothy, Adams, Danielle, Ricker, Austin, Patel, Nishit, Kühne, Andreas, Hughes, Simon, Shiffman, Dan, Zimmermann, Dirk, te Kaat, Kai, Rothmann, Thomas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441096/
https://ncbi.nlm.nih.gov/pubmed/28532404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3328-z
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