Use of the QIAGEN GeneReader NGS system for detection of KRAS mutations, validated by the QIAGEN Therascreen PCR kit and alternative NGS platform

BACKGROUND: The detection of somatic mutations in primary tumors is critical for the understanding of cancer evolution and targeting therapy. Multiple technologies have been developed to enable the detection of such mutations. Next generation sequencing (NGS) is a new platform that is gradually beco...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:BMC Cancer
المؤلفون الرئيسيون: Darwanto, Agus, Hein, Anne-Mette, Strauss, Sascha, Kong, Yi, Sheridan, Andrew, Richards, Dan, Lader, Eric, Ngowe, Monika, Pelletier, Timothy, Adams, Danielle, Ricker, Austin, Patel, Nishit, Kühne, Andreas, Hughes, Simon, Shiffman, Dan, Zimmermann, Dirk, te Kaat, Kai, Rothmann, Thomas
التنسيق: Artigo
اللغة:Inglês
منشور في: BioMed Central 2017
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441096/
https://ncbi.nlm.nih.gov/pubmed/28532404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3328-z
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