Validation of an NGS mutation detection panel for melanoma

BACKGROUND: Knowledge of the genotype of melanoma is important to guide patient management. Identification of mutations in BRAF and c-KIT lead directly to targeted treatment, but it is also helpful to know if there are driver oncogene mutations in NRAS, GNAQ or GNA11 as these patients may benefit fr...

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Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Reiman, Anne, Kikuchi, Hugh, Scocchia, Daniela, Smith, Peter, Tsang, Yee Wah, Snead, David, Cree, Ian A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322598/
https://ncbi.nlm.nih.gov/pubmed/28228113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3149-0
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