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Key considerations for comprehensive validation of an RNA fusion NGS panel

OBJECTIVES: Validation of RNA-based NGS assays for the detection of therapeutically targetable gene fusions is challenging. Here, we report systematic validation and quality control monitoring of our targeted fusion panel for the detection of 17 clinically relevant fusion transcripts across several...

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Detalhes bibliográficos
Publicado no:Pract Lab Med
Main Authors: Barua, Subit, Wang, Gary, Mansukhani, Mahesh, Hsiao, Susan, Fernandes, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322345/
https://ncbi.nlm.nih.gov/pubmed/32613069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plabm.2020.e00173
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