p16(INK4a), a Senescence Marker, Influences Tenofovir/Emtricitabine Metabolite Disposition in HIV‐Infected Subjects

The goal of this study was to explore the relationships between tenofovir (TFV) and emtricitabine (FTC) disposition and markers of biologic aging, such as the frailty phenotype and p16(INK4a) gene expression. Chronologic age is often explored in population pharmacokinetic (PK) analyses, and can be u...

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Bibliografske podrobnosti
izdano v:CPT Pharmacometrics Syst Pharmacol
Main Authors: Dumond, JB, Collins, JW, Cottrell, ML, Trezza, CR, Prince, HMA, Sykes, C, Torrice, C, White, N, Malone, S, Wang, R, Patterson, KB, Sharpless, NE, Forrest, A
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321809/
https://ncbi.nlm.nih.gov/pubmed/28019088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12150
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