Intracellular Tenofovir and Emtricitabine Concentrations in Younger and Older Women with HIV Receiving Tenofovir Disoproxil Fumarate/Emtricitabine

The altered immune states of aging and HIV infection may affect intracellular metabolism of tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC); increased cellular senescence decreases FTC-triphosphate (FTCtp) concentrations. The effects of age and inflammation on the ratio of intracellular...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Dumond, Julie B., Bay, Camden P., Nelson, Julie A. E., Davalos, Angel, Edmonds, Andrew, De Paris, Kristina, Sykes, Craig, Anastos, Kathryn, Sharma, Roopali, Kassaye, Seble, Tamraz, Bani, French, Audrey L., Gange, Stephen, Ofotokun, Ighovwerha, Fischl, Margaret A., Vance, David E., Adimora, Adaora A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449168/
https://ncbi.nlm.nih.gov/pubmed/32631821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00177-20
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