Intracellular Tenofovir and Emtricitabine Concentrations in Younger and Older Women with HIV Receiving Tenofovir Disoproxil Fumarate/Emtricitabine

The altered immune states of aging and HIV infection may affect intracellular metabolism of tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC); increased cellular senescence decreases FTC-triphosphate (FTCtp) concentrations. The effects of age and inflammation on the ratio of intracellular...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Dumond, Julie B., Bay, Camden P., Nelson, Julie A. E., Davalos, Angel, Edmonds, Andrew, De Paris, Kristina, Sykes, Craig, Anastos, Kathryn, Sharma, Roopali, Kassaye, Seble, Tamraz, Bani, French, Audrey L., Gange, Stephen, Ofotokun, Ighovwerha, Fischl, Margaret A., Vance, David E., Adimora, Adaora A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449168/
https://ncbi.nlm.nih.gov/pubmed/32631821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00177-20
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