Intracellular Tenofovir and Emtricitabine Concentrations in Younger and Older Women with HIV Receiving Tenofovir Disoproxil Fumarate/Emtricitabine

The altered immune states of aging and HIV infection may affect intracellular metabolism of tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC); increased cellular senescence decreases FTC-triphosphate (FTCtp) concentrations. The effects of age and inflammation on the ratio of intracellular...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Dumond, Julie B., Bay, Camden P., Nelson, Julie A. E., Davalos, Angel, Edmonds, Andrew, De Paris, Kristina, Sykes, Craig, Anastos, Kathryn, Sharma, Roopali, Kassaye, Seble, Tamraz, Bani, French, Audrey L., Gange, Stephen, Ofotokun, Ighovwerha, Fischl, Margaret A., Vance, David E., Adimora, Adaora A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449168/
https://ncbi.nlm.nih.gov/pubmed/32631821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00177-20
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