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Return to quiescence of murine neural stem cells by degradation of a pro-activation protein
Quiescence is essential for long-term maintenance of adult stem cells. Niche signals regulate the transit of stem cells from dormant to activated states. Here we show that the E3-ubiquitin ligase Huwe1 (HECT, UBA and WWE domain containing 1) is required for proliferating stem cells of the adult mous...
Tallennettuna:
| Julkaisussa: | Science |
|---|---|
| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5321528/ https://ncbi.nlm.nih.gov/pubmed/27418510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf4802 |
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