Id4 promotes the elimination of the pro-activation factor Ascl1 to maintain quiescence of adult hippocampal stem cells

Quiescence is essential for the long-term maintenance of adult stem cells but how stem cells maintain quiescence is poorly understood. Here, we show that neural stem cells (NSCs) in the adult mouse hippocampus actively transcribe the pro-activation factor Ascl1 regardless of their activated or quies...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Blomfield, Isabelle Maria, Rocamonde, Brenda, Masdeu, Maria del Mar, Mulugeta, Eskeatnaf, Vaga, Stefania, van den Berg, Debbie LC, Huillard, Emmanuelle, Guillemot, François, Urbán, Noelia
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2019
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805120/
https://ncbi.nlm.nih.gov/pubmed/31552825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48561
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