Epigenomic enhancer annotation reveals a key role for NFIX in neural stem cell quiescence

The majority of neural stem cells (NSCs) in the adult brain are quiescent, and this fraction increases with aging. Although signaling pathways that promote NSC quiescence have been identified, the transcriptional mechanisms involved are mostly unknown, largely due to lack of a cell culture model. In...

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Autors principals: Martynoga, Ben, Mateo, Juan L., Zhou, Bo, Andersen, Jimena, Achimastou, Angeliki, Urbán, Noelia, van den Berg, Debbie, Georgopoulou, Dimitra, Hadjur, Suzana, Wittbrodt, Joachim, Ettwiller, Laurence, Piper, Michael, Gronostajski, Richard M., Guillemot, François
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2013
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759694/
https://ncbi.nlm.nih.gov/pubmed/23964093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.216804.113
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