B-type receptor for platelet-derived growth factor mediates a chemotactic response by means of ligand-induced activation of the receptor protein-tyrosine kinase.

Porcine aorta endothelial cells are devoid of receptors for platelet-derived growth factor (PDGF). We have transfected such cells with cDNA for the PDGF B-type receptor, both the wild-type receptor and a mutant form of the receptor (K634A), in which the putative nucleotide-binding lysine of the prot...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Westermark, B, Siegbahn, A, Heldin, C H, Claesson-Welsh, L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53213/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153283/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.1.128
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