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ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence
Chikungunya virus (CHIKV), an Old World alphavirus, is transmitted to humans by infected mosquitoes and causes acute rash and arthritis, occasionally complicated by neurologic disease and chronic arthritis. One determinant of alphavirus virulence is nonstructural protein 3 (nsP3) that contains a hig...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5321000/ https://ncbi.nlm.nih.gov/pubmed/28143925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621485114 |
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