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ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence
Chikungunya virus (CHIKV), an Old World alphavirus, is transmitted to humans by infected mosquitoes and causes acute rash and arthritis, occasionally complicated by neurologic disease and chronic arthritis. One determinant of alphavirus virulence is nonstructural protein 3 (nsP3) that contains a hig...
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| I publikationen: | Proc Natl Acad Sci U S A |
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| Huvudupphovsmän: | , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2017
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5321000/ https://ncbi.nlm.nih.gov/pubmed/28143925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621485114 |
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