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Preparation of Recombinant Alphaviruses for Functional Studies of ADP-Ribosylation
Recently we characterized the mono(ADP-ribosyl) hydrolase (MAR hydrolase) activity of the macrodomain of nonstructural protein 3 (nsP3(MD)) of chikungunya virus. Using recombinant viruses with targeted mutations in the macrodomain, we demonstrated that hydrolase function is important for viral repli...
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| Publicado no: | ADP-ribosylation and NAD+ Utilizing Enzymes |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6382469/ https://ncbi.nlm.nih.gov/pubmed/30097877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-8588-3_21 |
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