Akt signaling is critical for memory CD8(+) T-cell development and tumor immune surveillance

Memory CD8(+) T cells confer long-term immunity against tumors, and anticancer vaccines therefore should maximize their generation. Multiple memory CD8(+) T-cell subsets with distinct functional and homing characteristics exist, but the signaling pathways that regulate their development are ill defi...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Rogel, Anne, Willoughby, Jane E., Buchan, Sarah L., Leonard, Henry J., Thirdborough, Stephen M., Al-Shamkhani, Aymen
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320983/
https://ncbi.nlm.nih.gov/pubmed/28137869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611299114
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