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Akt signaling is critical for memory CD8(+) T-cell development and tumor immune surveillance
Memory CD8(+) T cells confer long-term immunity against tumors, and anticancer vaccines therefore should maximize their generation. Multiple memory CD8(+) T-cell subsets with distinct functional and homing characteristics exist, but the signaling pathways that regulate their development are ill defi...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5320983/ https://ncbi.nlm.nih.gov/pubmed/28137869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611299114 |
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