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NFκB–Pim-1–Eomesodermin axis is critical for maintaining CD8 T-cell memory quality
T-cell memory is critical for long-term immunity. However, the factors involved in maintaining the persistence, function, and phenotype of the memory pool are undefined. Eomesodermin (Eomes) is required for the establishment of the memory pool. Here, we show that in T cells transitioning to memory,...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338529/ https://ncbi.nlm.nih.gov/pubmed/28193872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608448114 |
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