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Distinct Motifs in the Intracellular Domain of Human CD30 Differentially Activate Canonical and Alternative Transcription Factor NF-κB Signaling

The TNF-receptor superfamily member CD30 is expressed on normal and malignant lymphocytes, including anaplastic large cell lymphoma (ALCL) cells. CD30 transmits multiple effects, including activation of NF-κB signaling, cell proliferation, growth arrest and apoptosis. How CD30 generates these pleiot...

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Detalhes bibliográficos
Main Authors: Buchan, Sarah L., Al-Shamkhani, Aymen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445475/
https://ncbi.nlm.nih.gov/pubmed/23028875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045244
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