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Generation of Gross Chromosomal Rearrangements by a Single Engineered DNA Double Strand Break
Gross chromosomal rearrangements (GCRs), including translocations, inversions amplifications, and deletions, can be causal events leading to malignant transformation. GCRs are thought to be triggered by DNA double strand breaks (DSBs), which in turn can be spontaneous or induced by external agents (...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5320478/ https://ncbi.nlm.nih.gov/pubmed/28225067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43156 |
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