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Generation of Gross Chromosomal Rearrangements by a Single Engineered DNA Double Strand Break
Gross chromosomal rearrangements (GCRs), including translocations, inversions amplifications, and deletions, can be causal events leading to malignant transformation. GCRs are thought to be triggered by DNA double strand breaks (DSBs), which in turn can be spontaneous or induced by external agents (...
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| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5320478/ https://ncbi.nlm.nih.gov/pubmed/28225067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43156 |
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