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Generation of Gross Chromosomal Rearrangements by a Single Engineered DNA Double Strand Break

Gross chromosomal rearrangements (GCRs), including translocations, inversions amplifications, and deletions, can be causal events leading to malignant transformation. GCRs are thought to be triggered by DNA double strand breaks (DSBs), which in turn can be spontaneous or induced by external agents (...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Qiu, Zhijun, Zhang, Zhenhua, Roschke, Anna, Varga, Tamas, Aplan, Peter D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320478/
https://ncbi.nlm.nih.gov/pubmed/28225067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43156
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