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Efficient repair of DNA double-strand breaks in malignant cells with structural instability
Aberrant repair of DNA double strand breaks (DSBs) is thought to be important in the generation of gross chromosomal rearrangements (GCRs). To examine how DNA DSBs might lead to GCRs, we investigated the repair of a single DNA DSB in a structurally unstable cell line. An I-SceI recognition site was...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797445/ https://ncbi.nlm.nih.gov/pubmed/19909760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2009.10.016 |
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