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Single CD28 stimulation induces stable and polyclonal expansion of human regulatory T cells
CD4+FOXP3+ Treg are essential for immune tolerance. Phase-1 clinical trials of Treg-therapy to treat graft-versus-host-disease reported safety and potential therapeutic efficacy. Treg-based trials have started in organ-transplant patients. However, efficient ex vivo expansion of a stable Treg popula...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5320448/ https://ncbi.nlm.nih.gov/pubmed/28223693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43003 |
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