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p116(Rip) Targets Myosin Phosphatase to the Actin Cytoskeleton and Is Essential for RhoA/ROCK-regulated Neuritogenesis

Activation of the RhoA-Rho kinase (ROCK) pathway stimulates actomyosin-driven contractility in many cell systems, largely through ROCK-mediated inhibition of myosin II light chain phosphatase. In neuronal cells, the RhoA-ROCK-actomyosin pathway signals cell rounding, growth cone collapse, and neurit...

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Autores principales: Mulder, Jacqueline, Ariaens, Aafke, van den Boomen, Dick, Moolenaar, Wouter H.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC532030/
https://ncbi.nlm.nih.gov/pubmed/15469989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-04-0275
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