RhoA/ROCK regulation of neuritogenesis via profilin IIa–mediated control of actin stability

Neuritogenesis, the first step of neuronal differentiation, takes place as nascent neurites bud from the immediate postmitotic neuronal soma. Little is known about the mechanisms underlying the dramatic morphological changes that characterize this event. Here, we show that RhoA activity plays a deci...

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Bibliographic Details
Main Authors: Da Silva, Jorge Santos, Medina, Miguel, Zuliani, Cecilia, Di Nardo, Alessia, Witke, Walter, Dotti, Carlos G.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2003
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173969/
https://ncbi.nlm.nih.gov/pubmed/14517206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200304021
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