An Intestinal Farnesoid X Receptor–Ceramide Signaling Axis Modulates Hepatic Gluconeogenesis in Mice

Increasing evidence supports the view that intestinal farnesoid X receptor (FXR) is involved in glucose tolerance and that FXR signaling can be profoundly impacted by the gut microbiota. Selective manipulation of the gut microbiota–FXR signaling axis was reported to significantly impact glucose into...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Xie, Cen, Jiang, Changtao, Shi, Jingmin, Gao, Xiaoxia, Sun, Dongxue, Sun, Lulu, Wang, Ting, Takahashi, Shogo, Anitha, Mallappa, Krausz, Kristopher W., Patterson, Andrew D., Gonzalez, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2017
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319721/
https://ncbi.nlm.nih.gov/pubmed/28223344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0663
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