An Intestinal Farnesoid X Receptor–Ceramide Signaling Axis Modulates Hepatic Gluconeogenesis in Mice

Increasing evidence supports the view that intestinal farnesoid X receptor (FXR) is involved in glucose tolerance and that FXR signaling can be profoundly impacted by the gut microbiota. Selective manipulation of the gut microbiota–FXR signaling axis was reported to significantly impact glucose into...

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Veröffentlicht in:Diabetes
Hauptverfasser: Xie, Cen, Jiang, Changtao, Shi, Jingmin, Gao, Xiaoxia, Sun, Dongxue, Sun, Lulu, Wang, Ting, Takahashi, Shogo, Anitha, Mallappa, Krausz, Kristopher W., Patterson, Andrew D., Gonzalez, Frank J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2017
Schlagworte:
Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5319721/
https://ncbi.nlm.nih.gov/pubmed/28223344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0663
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