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Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes
Type 1 diabetes results from chronic autoimmune destruction of insulin-producing β-cells within pancreatic islets. Although insulin is a critical self-antigen in animal models of autoimmune diabetes, due to extremely limited access to pancreas samples, little is known about human antigenic targets f...
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| Udgivet i: | Diabetes |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Diabetes Association
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5319719/ https://ncbi.nlm.nih.gov/pubmed/27920090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-1025 |
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