Structure-based selection of small molecules to alter allele-specific MHC class II antigen presentation

Class II major histocompatability molecules are the primary susceptibility locus for many autoimmune disorders including type 1 diabetes. Human DQ8 and I-A(g7), in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes, confers diabetes risk by modulating presentation of specifi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Michels, Aaron W, Ostrov, David A, Zhang, Li, Nakayama, Maki, Fuse, Masanori, McDaniel, Kristen, Roep, Bart O, Gottlieb, Peter A, Atkinson, Mark A, Eisenbarth, George S
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221928/
https://ncbi.nlm.nih.gov/pubmed/22043012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100746
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados