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MHC class II molecules on the move for successful antigen presentation

Major histocompatibility complex class II (MHC II) molecules are targeted to endocytic compartments, known as MIIC, by the invariant chain (Ii) that is degraded upon arrival in these compartments. MHC II acquire antigenic fragments from endocytosed proteins for presentation at the cell surface. In a...

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Autores principales: Rocha, Nuno, Neefjes, Jacques
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206127/
https://ncbi.nlm.nih.gov/pubmed/18046453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601945
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