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MHC class II molecules on the move for successful antigen presentation
Major histocompatibility complex class II (MHC II) molecules are targeted to endocytic compartments, known as MIIC, by the invariant chain (Ii) that is degraded upon arrival in these compartments. MHC II acquire antigenic fragments from endocytosed proteins for presentation at the cell surface. In a...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206127/ https://ncbi.nlm.nih.gov/pubmed/18046453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601945 |
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