The first step of peptide selection in antigen presentation by MHC class I molecules

MHC class I molecules present a variable but limited repertoire of antigenic peptides for T-cell recognition. Understanding how peptide selection is achieved requires mechanistic insights into the interactions between the MHC I and candidate peptides. We find that, at first encounter, MHC I H-2K(b)...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Garstka, Malgorzata A., Fish, Alexander, Celie, Patrick H. N., Joosten, Robbie P., Janssen, George M. C., Berlin, Ilana, Hoppes, Rieuwert, Stadnik, Magda, Janssen, Lennert, Ovaa, Huib, van Veelen, Peter A., Perrakis, Anastassis, Neefjes, Jacques
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321303/
https://ncbi.nlm.nih.gov/pubmed/25605945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416543112
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