The first step of peptide selection in antigen presentation by MHC class I molecules

MHC class I molecules present a variable but limited repertoire of antigenic peptides for T-cell recognition. Understanding how peptide selection is achieved requires mechanistic insights into the interactions between the MHC I and candidate peptides. We find that, at first encounter, MHC I H-2K(b)...

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Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Garstka, Malgorzata A., Fish, Alexander, Celie, Patrick H. N., Joosten, Robbie P., Janssen, George M. C., Berlin, Ilana, Hoppes, Rieuwert, Stadnik, Magda, Janssen, Lennert, Ovaa, Huib, van Veelen, Peter A., Perrakis, Anastassis, Neefjes, Jacques
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2015
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321303/
https://ncbi.nlm.nih.gov/pubmed/25605945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416543112
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