The first step of peptide selection in antigen presentation by MHC class I molecules

MHC class I molecules present a variable but limited repertoire of antigenic peptides for T-cell recognition. Understanding how peptide selection is achieved requires mechanistic insights into the interactions between the MHC I and candidate peptides. We find that, at first encounter, MHC I H-2K(b)...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Garstka, Malgorzata A., Fish, Alexander, Celie, Patrick H. N., Joosten, Robbie P., Janssen, George M. C., Berlin, Ilana, Hoppes, Rieuwert, Stadnik, Magda, Janssen, Lennert, Ovaa, Huib, van Veelen, Peter A., Perrakis, Anastassis, Neefjes, Jacques
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2015
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321303/
https://ncbi.nlm.nih.gov/pubmed/25605945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416543112
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