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Cancer Cell Mitochondria Targeting by Pancratistatin Analogs is Dependent on Functional Complex II and III

Enhanced mitochondrial stability and decreased dependence on oxidative phosphorylation confer an acquired resistance to apoptosis in cancer cells, but may present opportunities for therapeutic intervention. The compound pancratistatin (PST) has been shown to selectively induce apoptosis in cancer ce...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Ma, Dennis, Pignanelli, Christopher, Tarade, Daniel, Gilbert, Tyler, Noel, Megan, Mansour, Fadi, Adams, Scott, Dowhayko, Alexander, Stokes, Kyle, Vshyvenko, Sergey, Hudlicky, Tomas, McNulty, James, Pandey, Siyaram
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318952/
https://ncbi.nlm.nih.gov/pubmed/28220885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42957
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