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Unnatural C-1 homologues of pancratistatin — Synthesis and promising biological activities

Several C-1 homologues of pancratistatin and 7-deoxypancratistatin were synthesized by a phenanthrene–phenathridone oxidative recyclization strategy. The key steps involved the enzymatic dihydroxylation of bromobenzene, addition of an aryl alane to an epoxyaziridine, an intramolecular aziridine open...

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Detalhes bibliográficos
Publicado no:Can J Chem
Main Authors: Vshyvenko, Sergey, Scattolon, Jon, Hudlicky, Tomas, Romero, Anntherese E., Kornienko, Alexander, Ma, Dennis, Tuffley, Ian, Pandey, Siyaram
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5176109/
https://ncbi.nlm.nih.gov/pubmed/28017970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/v2012-073
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