Informing efficient randomised controlled trials: exploration of challenges in developing progression criteria for internal pilot studies

OBJECTIVES: Designing studies with an internal pilot phase may optimise the use of pilot work to inform more efficient randomised controlled trials (RCTs). Careful selection of preagreed decision or ‘progression’ criteria at the juncture between the internal pilot and main trial phases provides a va...

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Vydáno v:BMJ Open
Hlavní autoři: Avery, Kerry N L, Williamson, Paula R, Gamble, Carrol, O'Connell Francischetto, Elaine, Metcalfe, Chris, Davidson, Peter, Williams, Hywel, Blazeby, Jane M
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2017
Témata:
Health Services Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318608/
https://ncbi.nlm.nih.gov/pubmed/28213598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2016-013537
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