Informing efficient randomised controlled trials: exploration of challenges in developing progression criteria for internal pilot studies

OBJECTIVES: Designing studies with an internal pilot phase may optimise the use of pilot work to inform more efficient randomised controlled trials (RCTs). Careful selection of preagreed decision or ‘progression’ criteria at the juncture between the internal pilot and main trial phases provides a va...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Avery, Kerry N L, Williamson, Paula R, Gamble, Carrol, O'Connell Francischetto, Elaine, Metcalfe, Chris, Davidson, Peter, Williams, Hywel, Blazeby, Jane M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Health Services Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318608/
https://ncbi.nlm.nih.gov/pubmed/28213598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2016-013537
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