S 38093, a histamine H(3) antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice

Strategies designed to increase adult hippocampal neurogenesis (AHN) may have therapeutic potential for reversing memory impairments. H(3) receptor antagonists/inverse agonists also may be useful for treating cognitive deficits. However, it remains unclear whether these ligands have effects on AHN....

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Publicat a:Sci Rep
Autors principals: Guilloux, Jean-Philippe, Samuels, Benjamin A., Mendez-David, Indira, Hu, Alice, Levinstein, Marjorie, Faye, Charlène, Mekiri, Maryam, Mocaer, Elisabeth, Gardier, Alain M., Hen, René, Sors, Aurore, David, Denis J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5317168/
https://ncbi.nlm.nih.gov/pubmed/28218311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42946
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