Preclinical concepts and results with the GABA(A) antagonist S44819 in a mouse model of middle cerebral artery occlusion

Por Hermann, Dirk M., Saba, Barbara, Sors, Aurore, Bassetti, Claudio L.
Publicado no Neural Regen Res (2019)

The Synergistic Enhancing-Memory Effect of Donepezil and S 38093 (a Histamine H(3) Antagonist) Is Mediated by Increased Neural Activity in the Septo-hippocampal Circuitry in Middle...

Por Sors, Aurore, Krazem, Ali, Kehr, Jan, Yoshitake, Takashi, Dominguez, Gaelle, Henkous, Nadia, Letondor, Claire, Mocaer, Elisabeth, Béracochéa, Daniel J.
Publicado no Front Pharmacol (2016)

Randomized Efficacy and Safety Trial with Oral S 44819 after Recent ischemic cerebral Event (RESTORE BRAIN study): a placebo controlled phase II study

Por Chabriat, Hugues, Bassetti, Claudio L., Marx, Ute, Picarel-Blanchot, Françoise, Sors, Aurore, Gruget, Celine, Saba, Barbara, Wattez, Marine, Audoli, Marie-Laure, Hermann, Dirk M.
Publicado no Trials (2020)

S 38093, a histamine H(3) antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice

Por Guilloux, Jean-Philippe, Samuels, Benjamin A., Mendez-David, Indira, Hu, Alice, Levinstein, Marjorie, Faye, Charlène, Mekiri, Maryam, Mocaer, Elisabeth, Gardier, Alain M., Hen, René, Sors, Aurore, David, Denis J.
Publicado no Sci Rep (2017)