Transposon mutagenesis identifies candidate genes that cooperate with loss of Transforming Growth Factor-beta signaling in mouse intestinal neoplasms

Colorectal cancer (CRC) results from the accumulation of gene mutations and epigenetic alterations in colon epithelial cells, which promotes CRC formation through deregulating signaling pathways. One of the most commonly deregulated signaling pathways in CRC is the transforming growth factor β (TGF-...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Morris, Shelli M., Davison, Jerry, Carter, Kelly T., O’Leary, Rachele M., Trobridge, Patty, Knoblaugh, Sue E., Myeroff, Lois L., Markowitz, Sanford D., Brett, Benjamin T., Scheetz, Todd E., Dupuy, Adam J., Starr, Timothy K., Grady, William M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316486/
https://ncbi.nlm.nih.gov/pubmed/27790711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30491
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