Transposon mutagenesis identifies candidate genes that cooperate with loss of Transforming Growth Factor-beta signaling in mouse intestinal neoplasms

Colorectal cancer (CRC) results from the accumulation of gene mutations and epigenetic alterations in colon epithelial cells, which promotes CRC formation through deregulating signaling pathways. One of the most commonly deregulated signaling pathways in CRC is the transforming growth factor β (TGF-...

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Publicat a:Int J Cancer
Autors principals: Morris, Shelli M., Davison, Jerry, Carter, Kelly T., O’Leary, Rachele M., Trobridge, Patty, Knoblaugh, Sue E., Myeroff, Lois L., Markowitz, Sanford D., Brett, Benjamin T., Scheetz, Todd E., Dupuy, Adam J., Starr, Timothy K., Grady, William M.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316486/
https://ncbi.nlm.nih.gov/pubmed/27790711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30491
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