Prospective Analysis in GIST Patients on the Role of Alpha-1 Acid Glycoprotein in Imatinib Exposure

BACKGROUND: For imatinib, a relationship between systemic exposure and clinical outcome has been suggested. Importantly, imatinib concentrations are not stable and decrease over time, for which several mechanisms have been suggested. In this study, we investigated if a decrease in alpha-1 acid glyco...

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Detaylı Bibliyografya
Yayımlandı:Clin Pharmacokinet
Asıl Yazarlar: Bins, Sander, Eechoute, Karel, Kloth, Jacqueline S. L., de Man, Femke M., Oosten, Astrid W., de Bruijn, Peter, Sleijfer, Stefan, Mathijssen, Ron H. J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer International Publishing 2016
Konular:
Short Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315737/
https://ncbi.nlm.nih.gov/pubmed/27461250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-016-0441-0
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