Prospective Analysis in GIST Patients on the Role of Alpha-1 Acid Glycoprotein in Imatinib Exposure

BACKGROUND: For imatinib, a relationship between systemic exposure and clinical outcome has been suggested. Importantly, imatinib concentrations are not stable and decrease over time, for which several mechanisms have been suggested. In this study, we investigated if a decrease in alpha-1 acid glyco...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Pharmacokinet
Päätekijät: Bins, Sander, Eechoute, Karel, Kloth, Jacqueline S. L., de Man, Femke M., Oosten, Astrid W., de Bruijn, Peter, Sleijfer, Stefan, Mathijssen, Ron H. J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer International Publishing 2016
Aiheet:
Short Communication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315737/
https://ncbi.nlm.nih.gov/pubmed/27461250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-016-0441-0
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