Prospective Analysis in GIST Patients on the Role of Alpha-1 Acid Glycoprotein in Imatinib Exposure

BACKGROUND: For imatinib, a relationship between systemic exposure and clinical outcome has been suggested. Importantly, imatinib concentrations are not stable and decrease over time, for which several mechanisms have been suggested. In this study, we investigated if a decrease in alpha-1 acid glyco...

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Bibliografische gegevens
Gepubliceerd in:Clin Pharmacokinet
Hoofdauteurs: Bins, Sander, Eechoute, Karel, Kloth, Jacqueline S. L., de Man, Femke M., Oosten, Astrid W., de Bruijn, Peter, Sleijfer, Stefan, Mathijssen, Ron H. J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2016
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Short Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5315737/
https://ncbi.nlm.nih.gov/pubmed/27461250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-016-0441-0
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