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Prospective Analysis in GIST Patients on the Role of Alpha-1 Acid Glycoprotein in Imatinib Exposure
BACKGROUND: For imatinib, a relationship between systemic exposure and clinical outcome has been suggested. Importantly, imatinib concentrations are not stable and decrease over time, for which several mechanisms have been suggested. In this study, we investigated if a decrease in alpha-1 acid glyco...
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Publicado no: | Clin Pharmacokinet |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer International Publishing
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5315737/ https://ncbi.nlm.nih.gov/pubmed/27461250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-016-0441-0 |
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