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The p53 inhibitor Mdm4 cooperates with multiple genetic lesions in tumorigenesis
The p53 inhibitor Mdm4 is present at high levels in multiple human cancers. Overexpression of Mdm4 in mice drives spontaneous development of mostly lymphomas and sarcomas. In this study, we explored the ability of Mdm4 to cooperate with other lesions in tumour development. The Mdm4 transgene contrib...
Gorde:
| Argitaratua izan da: | J Pathol |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5315583/ https://ncbi.nlm.nih.gov/pubmed/27925213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4854 |
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